Analysis Type:	PANTHER Overrepresentation Test (Released 20181113)
Annotation Version and Release Date:	GO Ontology database  Released 2018-10-08
Analyzed List:	T6C1_DOWN_0.1.genes (Homo sapiens)	There are duplicate IDs in the file. The unique set of IDs will be used.
Reference List:	background.genes (Homo sapiens)	There are duplicate IDs in the file. The unique set of IDs will be used.
Test Type:	FISHER
Correction:	FDR
GO biological process complete	background.genes - REFLIST (15398)	T6C1_DOWN_0.1.genes (1249)	T6C1_DOWN_0.1.genes (expected)	T6C1_DOWN_0.1.genes (over/under)	T6C1_DOWN_0.1.genes (fold Enrichment)	T6C1_DOWN_0.1.genes (raw P-value)	T6C1_DOWN_0.1.genes (FDR)
trophoblast giant cell differentiation (GO:0060707)	10	6	.81	+	7.40	7.32E-04	3.70E-02
cell-substrate junction assembly (GO:0007044)	38	14	3.08	+	4.54	1.97E-05	1.69E-03
negative regulation of organ growth (GO:0046621)	27	9	2.19	+	4.11	1.08E-03	4.96E-02
skeletal muscle cell differentiation (GO:0035914)	38	11	3.08	+	3.57	8.31E-04	4.06E-02
positive regulation of blood vessel diameter (GO:0097755)	42	12	3.41	+	3.52	5.39E-04	2.90E-02
regulation of focal adhesion assembly (GO:0051893)	58	16	4.70	+	3.40	9.64E-05	6.78E-03
regulation of cell-substrate junction assembly (GO:0090109)	58	16	4.70	+	3.40	9.64E-05	6.75E-03
regulation of adherens junction organization (GO:1903391)	64	17	5.19	+	3.27	8.75E-05	6.30E-03
positive regulation of actin filament bundle assembly (GO:0032233)	57	15	4.62	+	3.24	2.44E-04	1.52E-02
endochondral bone morphogenesis (GO:0060350)	56	14	4.54	+	3.08	6.02E-04	3.15E-02
regulation of cell junction assembly (GO:1901888)	82	20	6.65	+	3.01	6.02E-05	4.49E-03
regulation of blood vessel diameter (GO:0097746)	87	21	7.06	+	2.98	4.53E-05	3.52E-03
regulation of tube diameter (GO:0035296)	87	21	7.06	+	2.98	4.53E-05	3.50E-03
adherens junction organization (GO:0034332)	72	17	5.84	+	2.91	2.92E-04	1.79E-02
regulation of actin filament bundle assembly (GO:0032231)	87	20	7.06	+	2.83	1.21E-04	8.24E-03
negative regulation of developmental growth (GO:0048640)	92	21	7.46	+	2.81	9.01E-05	6.43E-03
regulation of blood vessel size (GO:0050880)	92	21	7.46	+	2.81	9.01E-05	6.40E-03
regulation of tube size (GO:0035150)	92	21	7.46	+	2.81	9.01E-05	6.37E-03
vascular process in circulatory system (GO:0003018)	116	26	9.41	+	2.76	1.81E-05	1.58E-03
lymphocyte activation involved in immune response (GO:0002285)	72	16	5.84	+	2.74	7.68E-04	3.81E-02
cell-matrix adhesion (GO:0007160)	109	24	8.84	+	2.71	7.80E-05	5.65E-03
regulation of actomyosin structure organization (GO:0110020)	83	18	6.73	+	2.67	4.76E-04	2.65E-02
homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)	136	29	11.03	+	2.63	1.63E-05	1.44E-03
platelet activation (GO:0030168)	109	23	8.84	+	2.60	1.52E-04	9.97E-03
cell-substrate adhesion (GO:0031589)	152	32	12.33	+	2.60	6.92E-06	7.26E-04
cell junction organization (GO:0034330)	180	37	14.60	+	2.53	2.78E-06	3.28E-04
cell junction assembly (GO:0034329)	142	29	11.52	+	2.52	2.93E-05	2.39E-03
multi-multicellular organism process (GO:0044706)	160	32	12.98	+	2.47	2.06E-05	1.75E-03
regulation of cell-matrix adhesion (GO:0001952)	105	21	8.52	+	2.47	4.85E-04	2.66E-02
negative regulation of secretion by cell (GO:1903531)	137	27	11.11	+	2.43	1.25E-04	8.47E-03
regulation of regulated secretory pathway (GO:1903305)	113	22	9.17	+	2.40	4.67E-04	2.61E-02
morphogenesis of a branching structure (GO:0001763)	124	24	10.06	+	2.39	3.88E-04	2.26E-02
lung development (GO:0030324)	131	25	10.63	+	2.35	3.11E-04	1.87E-02
circulatory system process (GO:0003013)	276	52	22.39	+	2.32	2.29E-07	3.95E-05
response to transforming growth factor beta (GO:0071559)	133	25	10.79	+	2.32	3.56E-04	2.11E-02
cellular response to transforming growth factor beta stimulus (GO:0071560)	128	24	10.38	+	2.31	4.92E-04	2.68E-02
hemostasis (GO:0007599)	225	42	18.25	+	2.30	5.23E-06	5.77E-04
respiratory system development (GO:0060541)	150	28	12.17	+	2.30	1.61E-04	1.05E-02
coagulation (GO:0050817)	220	41	17.85	+	2.30	7.29E-06	7.59E-04
blood coagulation (GO:0007596)	220	41	17.85	+	2.30	7.29E-06	7.53E-04
respiratory tube development (GO:0030323)	135	25	10.95	+	2.28	4.12E-04	2.34E-02
morphogenesis of a branching epithelium (GO:0061138)	119	22	9.65	+	2.28	1.01E-03	4.76E-02
regulation of cell shape (GO:0008360)	141	26	11.44	+	2.27	3.25E-04	1.95E-02
positive regulation of cell migration (GO:0030335)	402	74	32.61	+	2.27	1.62E-09	5.40E-07
regulation of blood pressure (GO:0008217)	125	23	10.14	+	2.27	7.80E-04	3.86E-02
regulation of Rho protein signal transduction (GO:0035023)	120	22	9.73	+	2.26	1.08E-03	4.97E-02
positive regulation of angiogenesis (GO:0045766)	137	25	11.11	+	2.25	4.82E-04	2.66E-02
negative regulation of secretion (GO:0051048)	154	28	12.49	+	2.24	2.96E-04	1.79E-02
blood vessel development (GO:0001568)	413	75	33.50	+	2.24	2.46E-09	7.86E-07
angiogenesis (GO:0001525)	270	49	21.90	+	2.24	1.48E-06	1.90E-04
blood vessel morphogenesis (GO:0048514)	342	62	27.74	+	2.23	8.08E-08	1.64E-05
positive regulation of GTPase activity (GO:0043547)	359	65	29.12	+	2.23	3.27E-08	7.77E-06
regulation of cell-substrate adhesion (GO:0010810)	177	32	14.36	+	2.23	9.94E-05	6.93E-03
lymphocyte differentiation (GO:0030098)	172	31	13.95	+	2.22	1.36E-04	9.09E-03
female pregnancy (GO:0007565)	139	25	11.27	+	2.22	8.00E-04	3.93E-02
extracellular matrix organization (GO:0030198)	256	46	20.77	+	2.22	4.07E-06	4.65E-04
regulation of GTPase activity (GO:0043087)	430	77	34.88	+	2.21	2.91E-09	9.10E-07
positive regulation of cell motility (GO:2000147)	416	74	33.74	+	2.19	8.12E-09	2.25E-06
blood circulation (GO:0008015)	270	48	21.90	+	2.19	4.18E-06	4.71E-04
regulation of exocytosis (GO:0017157)	164	29	13.30	+	2.18	2.92E-04	1.79E-02
ameboidal-type cell migration (GO:0001667)	148	26	12.00	+	2.17	7.03E-04	3.57E-02
positive regulation of cellular component movement (GO:0051272)	428	75	34.72	+	2.16	8.21E-09	2.24E-06
positive regulation of cell adhesion (GO:0045785)	314	55	25.47	+	2.16	1.03E-06	1.41E-04
synapse organization (GO:0050808)	217	38	17.60	+	2.16	5.56E-05	4.19E-03
negative regulation of growth (GO:0045926)	218	38	17.68	+	2.15	5.78E-05	4.33E-03
vasculature development (GO:0001944)	435	75	35.28	+	2.13	1.67E-08	4.24E-06
positive regulation of vasculature development (GO:1904018)	151	26	12.25	+	2.12	8.47E-04	4.11E-02
wound healing (GO:0042060)	362	62	29.36	+	2.11	4.83E-07	7.03E-05
extracellular structure organization (GO:0043062)	287	49	23.28	+	2.10	7.81E-06	8.02E-04
cell-cell adhesion (GO:0098609)	387	66	31.39	+	2.10	1.68E-07	3.07E-05
positive regulation of locomotion (GO:0040017)	443	75	35.93	+	2.09	3.56E-08	8.20E-06
cell adhesion (GO:0007155)	727	123	58.97	+	2.09	9.78E-13	8.62E-10
cardiovascular system development (GO:0072358)	444	75	36.01	+	2.08	3.70E-08	8.28E-06
tube morphogenesis (GO:0035239)	534	90	43.32	+	2.08	1.43E-09	4.88E-07
biological adhesion (GO:0022610)	732	123	59.38	+	2.07	1.21E-12	9.57E-10
positive regulation of supramolecular fiber organization (GO:1902905)	180	30	14.60	+	2.05	8.02E-04	3.93E-02
axon guidance (GO:0007411)	199	33	16.14	+	2.04	3.63E-04	2.14E-02
neuron projection guidance (GO:0097485)	200	33	16.22	+	2.03	3.82E-04	2.24E-02
muscle cell differentiation (GO:0042692)	188	31	15.25	+	2.03	6.45E-04	3.34E-02
positive regulation of cell-cell adhesion (GO:0022409)	188	31	15.25	+	2.03	6.45E-04	3.32E-02
muscle tissue development (GO:0060537)	225	37	18.25	+	2.03	1.99E-04	1.28E-02
cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742)	201	33	16.30	+	2.02	4.02E-04	2.31E-02
regulation of small GTPase mediated signal transduction (GO:0051056)	303	49	24.58	+	1.99	2.31E-05	1.93E-03
response to wounding (GO:0009611)	434	70	35.20	+	1.99	4.65E-07	6.84E-05
tissue morphogenesis (GO:0048729)	423	68	34.31	+	1.98	8.10E-07	1.12E-04
regulation of Ras protein signal transduction (GO:0046578)	206	33	16.71	+	1.97	7.02E-04	3.59E-02
heart development (GO:0007507)	412	66	33.42	+	1.97	1.42E-06	1.87E-04
tube development (GO:0035295)	675	108	54.75	+	1.97	4.01E-10	1.72E-07
regulation of cell migration (GO:0030334)	683	109	55.40	+	1.97	4.58E-10	1.85E-07
lymphocyte activation (GO:0046649)	282	45	22.87	+	1.97	7.19E-05	5.28E-03
regulation of vesicle-mediated transport (GO:0060627)	422	67	34.23	+	1.96	1.30E-06	1.74E-04
chemotaxis (GO:0006935)	386	61	31.31	+	1.95	6.26E-06	6.66E-04
regulation of anatomical structure size (GO:0090066)	431	68	34.96	+	1.95	1.55E-06	1.95E-04
regulation of leukocyte differentiation (GO:1902105)	203	32	16.47	+	1.94	1.02E-03	4.80E-02
regulation of supramolecular fiber organization (GO:1902903)	324	51	26.28	+	1.94	3.81E-05	3.00E-03
taxis (GO:0042330)	388	61	31.47	+	1.94	6.56E-06	6.93E-04
regulation of cell adhesion (GO:0030155)	535	84	43.40	+	1.94	9.01E-08	1.80E-05
cell morphogenesis (GO:0000902)	555	87	45.02	+	1.93	6.17E-08	1.34E-05
striated muscle tissue development (GO:0014706)	217	34	17.60	+	1.93	9.51E-04	4.54E-02
regulation of cell motility (GO:2000145)	729	114	59.13	+	1.93	4.37E-10	1.82E-07
circulatory system development (GO:0072359)	710	111	57.59	+	1.93	9.24E-10	3.38E-07
muscle structure development (GO:0061061)	371	58	30.09	+	1.93	1.06E-05	1.03E-03
regulation of body fluid levels (GO:0050878)	365	57	29.61	+	1.93	1.35E-05	1.27E-03
neuron projection morphogenesis (GO:0048812)	379	59	30.74	+	1.92	1.22E-05	1.15E-03
cell migration (GO:0016477)	656	102	53.21	+	1.92	5.07E-09	1.49E-06
regulation of angiogenesis (GO:0045765)	238	37	19.31	+	1.92	4.78E-04	2.64E-02
regulation of cell-cell adhesion (GO:0022407)	296	46	24.01	+	1.92	1.05E-04	7.27E-03
regulation of actin filament organization (GO:0110053)	245	38	19.87	+	1.91	5.41E-04	2.90E-02
regulation of endocytosis (GO:0030100)	220	34	17.85	+	1.91	1.03E-03	4.79E-02
leukocyte differentiation (GO:0002521)	246	38	19.95	+	1.90	5.55E-04	2.95E-02
regulation of ERK1 and ERK2 cascade (GO:0070372)	240	37	19.47	+	1.90	7.29E-04	3.69E-02
plasma membrane bounded cell projection morphogenesis (GO:0120039)	383	59	31.07	+	1.90	1.39E-05	1.29E-03
regulation of anatomical structure morphogenesis (GO:0022603)	838	129	67.97	+	1.90	8.51E-11	4.55E-08
positive regulation of leukocyte activation (GO:0002696)	234	36	18.98	+	1.90	6.69E-04	3.43E-02
actin filament-based process (GO:0030029)	475	73	38.53	+	1.89	1.36E-06	1.81E-04
cell projection morphogenesis (GO:0048858)	384	59	31.15	+	1.89	1.45E-05	1.32E-03
cell part morphogenesis (GO:0032990)	405	62	32.85	+	1.89	1.02E-05	1.01E-03
negative regulation of response to external stimulus (GO:0032102)	242	37	19.63	+	1.88	7.64E-04	3.81E-02
positive regulation of cell activation (GO:0050867)	243	37	19.71	+	1.88	7.86E-04	3.88E-02
regulation of secretion by cell (GO:1903530)	526	80	42.67	+	1.88	5.89E-07	8.41E-05
epithelial tube morphogenesis (GO:0060562)	237	36	19.22	+	1.87	1.02E-03	4.80E-02
regulation of cellular component movement (GO:0051270)	797	121	64.65	+	1.87	6.27E-10	2.35E-07
locomotion (GO:0040011)	931	141	75.52	+	1.87	2.62E-11	1.64E-08
regulation of trans-synaptic signaling (GO:0099177)	344	52	27.90	+	1.86	6.71E-05	4.96E-03
cell morphogenesis involved in differentiation (GO:0000904)	437	66	35.45	+	1.86	9.34E-06	9.39E-04
axon development (GO:0061564)	318	48	25.79	+	1.86	1.73E-04	1.12E-02
axonogenesis (GO:0007409)	285	43	23.12	+	1.86	4.10E-04	2.35E-02
regulation of locomotion (GO:0040012)	789	119	64.00	+	1.86	1.21E-09	4.22E-07
regulation of cell morphogenesis (GO:0022604)	425	64	34.47	+	1.86	1.11E-05	1.07E-03
regulation of vasculature development (GO:1901342)	259	39	21.01	+	1.86	7.56E-04	3.78E-02
cellular component morphogenesis (GO:0032989)	632	95	51.26	+	1.85	7.73E-08	1.61E-05
regulation of secretion (GO:0051046)	568	85	46.07	+	1.84	4.61E-07	6.84E-05
modulation of chemical synaptic transmission (GO:0050804)	343	51	27.82	+	1.83	1.37E-04	9.10E-03
morphogenesis of an epithelium (GO:0002009)	324	48	26.28	+	1.83	2.06E-04	1.31E-02
localization of cell (GO:0051674)	737	109	59.78	+	1.82	1.97E-08	4.91E-06
cell motility (GO:0048870)	737	109	59.78	+	1.82	1.97E-08	4.83E-06
regulation of cell activation (GO:0050865)	399	59	32.36	+	1.82	4.38E-05	3.42E-03
regulation of actin cytoskeleton organization (GO:0032956)	306	45	24.82	+	1.81	4.35E-04	2.45E-02
positive regulation of MAPK cascade (GO:0043410)	429	63	34.80	+	1.81	2.65E-05	2.18E-03
regulation of leukocyte activation (GO:0002694)	368	54	29.85	+	1.81	1.08E-04	7.45E-03
cell morphogenesis involved in neuron differentiation (GO:0048667)	335	49	27.17	+	1.80	2.52E-04	1.57E-02
actin cytoskeleton organization (GO:0030036)	426	62	34.55	+	1.79	5.11E-05	3.91E-03
regulation of peptide secretion (GO:0002791)	337	49	27.34	+	1.79	2.68E-04	1.66E-02
regulation of neuron projection development (GO:0010975)	428	62	34.72	+	1.79	5.29E-05	4.01E-03
cell activation (GO:0001775)	816	118	66.19	+	1.78	1.39E-08	3.60E-06
regulation of cell projection organization (GO:0031344)	581	84	47.13	+	1.78	2.60E-06	3.14E-04
negative regulation of transport (GO:0051051)	360	52	29.20	+	1.78	2.00E-04	1.28E-02
regulation of plasma membrane bounded cell projection organization (GO:0120035)	575	83	46.64	+	1.78	2.41E-06	2.96E-04
import into cell (GO:0098657)	514	74	41.69	+	1.77	9.94E-06	9.94E-04
regulation of protein secretion (GO:0050708)	320	46	25.96	+	1.77	5.76E-04	3.03E-02
anatomical structure formation involved in morphogenesis (GO:0048646)	691	99	56.05	+	1.77	3.51E-07	5.60E-05
inflammatory response (GO:0006954)	322	46	26.12	+	1.76	6.07E-04	3.16E-02
endocytosis (GO:0006897)	437	62	35.45	+	1.75	8.98E-05	6.44E-03
anatomical structure morphogenesis (GO:0009653)	1633	231	132.46	+	1.74	2.56E-15	5.48E-12
regulation of cell growth (GO:0001558)	361	51	29.28	+	1.74	4.11E-04	2.34E-02
regulation of actin filament-based process (GO:0032970)	340	48	27.58	+	1.74	5.87E-04	3.08E-02
neuron projection development (GO:0031175)	537	75	43.56	+	1.72	2.16E-05	1.82E-03
leukocyte activation (GO:0045321)	703	98	57.02	+	1.72	1.25E-06	1.69E-04
enzyme linked receptor protein signaling pathway (GO:0007167)	574	80	46.56	+	1.72	1.36E-05	1.27E-03
positive regulation of protein phosphorylation (GO:0001934)	778	108	63.11	+	1.71	3.78E-07	5.91E-05
tissue development (GO:0009888)	1205	167	97.74	+	1.71	1.98E-10	8.98E-08
central nervous system development (GO:0007417)	736	102	59.70	+	1.71	1.05E-06	1.43E-04
regulation of cellular component size (GO:0032535)	348	48	28.23	+	1.70	9.50E-04	4.55E-02
positive regulation of phosphorylation (GO:0042327)	821	113	66.59	+	1.70	3.60E-07	5.69E-05
negative regulation of protein phosphorylation (GO:0001933)	349	48	28.31	+	1.70	9.75E-04	4.62E-02
negative regulation of protein modification process (GO:0031400)	511	70	41.45	+	1.69	7.68E-05	5.61E-03
positive regulation of intracellular signal transduction (GO:1902533)	841	115	68.22	+	1.69	3.48E-07	5.67E-05
cytokine-mediated signaling pathway (GO:0019221)	447	61	36.26	+	1.68	2.95E-04	1.79E-02
movement of cell or subcellular component (GO:0006928)	1122	153	91.01	+	1.68	3.47E-09	1.04E-06
regulation of neurogenesis (GO:0050767)	664	90	53.86	+	1.67	1.01E-05	9.99E-04
brain development (GO:0007420)	569	77	46.15	+	1.67	4.83E-05	3.72E-03
positive regulation of phosphorus metabolic process (GO:0010562)	874	118	70.89	+	1.66	4.06E-07	6.27E-05
positive regulation of phosphate metabolic process (GO:0045937)	874	118	70.89	+	1.66	4.06E-07	6.21E-05
neuron development (GO:0048666)	645	87	52.32	+	1.66	1.52E-05	1.36E-03
regulation of protein serine/threonine kinase activity (GO:0071900)	424	57	34.39	+	1.66	5.68E-04	3.01E-02
head development (GO:0060322)	605	81	49.07	+	1.65	4.21E-05	3.31E-03
cellular response to growth factor stimulus (GO:0071363)	404	54	32.77	+	1.65	8.37E-04	4.07E-02
positive regulation of hydrolase activity (GO:0051345)	659	88	53.45	+	1.65	2.43E-05	2.03E-03
regulation of cell development (GO:0060284)	757	101	61.40	+	1.64	5.26E-06	5.76E-04
positive regulation of kinase activity (GO:0033674)	465	62	37.72	+	1.64	3.87E-04	2.26E-02
cell activation involved in immune response (GO:0002263)	481	64	39.02	+	1.64	3.47E-04	2.06E-02
epithelium development (GO:0060429)	718	95	58.24	+	1.63	1.50E-05	1.35E-03
response to growth factor (GO:0070848)	424	56	34.39	+	1.63	1.06E-03	4.89E-02
leukocyte activation involved in immune response (GO:0002366)	477	63	38.69	+	1.63	4.51E-04	2.53E-02
positive regulation of developmental process (GO:0051094)	1063	140	86.22	+	1.62	1.07E-07	2.04E-05
regulation of MAPK cascade (GO:0043408)	601	79	48.75	+	1.62	1.01E-04	6.98E-03
negative regulation of developmental process (GO:0051093)	732	96	59.38	+	1.62	1.79E-05	1.57E-03
nervous system development (GO:0007399)	1853	243	150.31	+	1.62	6.86E-13	6.43E-10
regulation of hydrolase activity (GO:0051336)	1062	139	86.14	+	1.61	1.93E-07	3.40E-05
animal organ morphogenesis (GO:0009887)	697	91	56.54	+	1.61	3.01E-05	2.44E-03
positive regulation of cell differentiation (GO:0045597)	766	100	62.13	+	1.61	1.48E-05	1.33E-03
negative regulation of multicellular organismal process (GO:0051241)	929	121	75.36	+	1.61	1.53E-06	1.95E-04
neurogenesis (GO:0022008)	1290	168	104.64	+	1.61	8.73E-09	2.34E-06
regulation of growth (GO:0040008)	576	75	46.72	+	1.61	1.85E-04	1.20E-02
regulation of nervous system development (GO:0051960)	745	97	60.43	+	1.61	2.10E-05	1.77E-03
regulation of cell differentiation (GO:0045595)	1391	181	112.83	+	1.60	2.35E-09	7.66E-07
negative regulation of cell differentiation (GO:0045596)	538	70	43.64	+	1.60	2.94E-04	1.79E-02
negative regulation of signal transduction (GO:0009968)	1030	134	83.55	+	1.60	4.45E-07	6.67E-05
negative regulation of cell communication (GO:0010648)	1101	143	89.31	+	1.60	1.68E-07	3.04E-05
regulation of neuron differentiation (GO:0045664)	539	70	43.72	+	1.60	3.88E-04	2.25E-02
negative regulation of signaling (GO:0023057)	1104	143	89.55	+	1.60	2.32E-07	3.91E-05
response to cytokine (GO:0034097)	788	102	63.92	+	1.60	1.43E-05	1.32E-03
regulation of intracellular signal transduction (GO:1902531)	1540	199	124.92	+	1.59	5.87E-10	2.32E-07
positive regulation of protein modification process (GO:0031401)	976	126	79.17	+	1.59	1.44E-06	1.88E-04
cell development (GO:0048468)	1255	162	101.80	+	1.59	3.49E-08	8.18E-06
regulation of developmental process (GO:0050793)	2022	261	164.01	+	1.59	3.64E-13	3.90E-10
regulation of protein phosphorylation (GO:0001932)	1147	148	93.04	+	1.59	1.54E-07	2.85E-05
generation of neurons (GO:0048699)	1210	155	98.15	+	1.58	9.70E-08	1.89E-05
regulation of localization (GO:0032879)	2139	274	173.50	+	1.58	1.87E-13	2.16E-10
negative regulation of response to stimulus (GO:0048585)	1309	167	106.18	+	1.57	3.58E-08	8.14E-06
negative regulation of cell proliferation (GO:0008285)	541	69	43.88	+	1.57	5.47E-04	2.92E-02
regulation of cellular component biogenesis (GO:0044087)	839	107	68.06	+	1.57	1.45E-05	1.32E-03
secretion by cell (GO:0032940)	769	98	62.38	+	1.57	3.73E-05	2.98E-03
positive regulation of multicellular organismal process (GO:0051240)	1311	167	106.34	+	1.57	4.74E-08	1.04E-05
regulation of multicellular organismal development (GO:2000026)	1578	201	128.00	+	1.57	1.20E-09	4.30E-07
animal organ development (GO:0048513)	2300	291	186.56	+	1.56	1.08E-13	1.35E-10
regulation of protein modification process (GO:0031399)	1503	190	121.91	+	1.56	7.72E-09	2.18E-06
regulation of transport (GO:0051049)	1409	178	114.29	+	1.56	2.31E-08	5.58E-06
exocytosis (GO:0006887)	635	80	51.51	+	1.55	2.74E-04	1.69E-02
secretion (GO:0046903)	843	106	68.38	+	1.55	3.39E-05	2.73E-03
cytoskeleton organization (GO:0007010)	947	119	76.82	+	1.55	1.04E-05	1.02E-03
regulation of response to external stimulus (GO:0032101)	582	73	47.21	+	1.55	6.26E-04	3.25E-02
regulated exocytosis (GO:0045055)	559	70	45.34	+	1.54	8.61E-04	4.15E-02
negative regulation of molecular function (GO:0044092)	895	112	72.60	+	1.54	1.93E-05	1.68E-03
system development (GO:0048731)	3318	415	269.14	+	1.54	7.31E-20	1.10E-15
regulation of protein kinase activity (GO:0045859)	657	82	53.29	+	1.54	3.34E-04	1.99E-02
regulation of phosphorylation (GO:0042325)	1248	155	101.23	+	1.53	5.79E-07	8.34E-05
regulation of kinase activity (GO:0043549)	725	90	58.81	+	1.53	2.16E-04	1.37E-02
neuron differentiation (GO:0030182)	767	95	62.21	+	1.53	1.44E-04	9.52E-03
intracellular signal transduction (GO:0035556)	1389	171	112.67	+	1.52	2.33E-07	3.88E-05
positive regulation of molecular function (GO:0044093)	1480	182	120.05	+	1.52	1.01E-07	1.94E-05
regulation of phosphate metabolic process (GO:0019220)	1417	174	114.94	+	1.51	2.25E-07	3.92E-05
regulation of phosphorus metabolic process (GO:0051174)	1419	174	115.10	+	1.51	2.30E-07	3.92E-05
positive regulation of catalytic activity (GO:0043085)	1192	146	96.69	+	1.51	2.95E-06	3.46E-04
regulation of cell proliferation (GO:0042127)	1240	151	100.58	+	1.50	2.62E-06	3.12E-04
regulation of signal transduction (GO:0009966)	2561	311	207.73	+	1.50	1.09E-12	9.11E-10
regulation of cell communication (GO:0010646)	2841	345	230.45	+	1.50	3.16E-14	4.74E-11
regulation of signaling (GO:0023051)	2874	349	233.12	+	1.50	2.25E-14	4.22E-11
positive regulation of signal transduction (GO:0009967)	1271	154	103.10	+	1.49	2.61E-06	3.13E-04
regulation of cellular component organization (GO:0051128)	2183	264	177.07	+	1.49	1.74E-10	8.41E-08
cell differentiation (GO:0030154)	2706	327	219.50	+	1.49	4.51E-13	4.50E-10
cellular response to cytokine stimulus (GO:0071345)	712	86	57.75	+	1.49	7.02E-04	3.58E-02
embryo development (GO:0009790)	737	89	59.78	+	1.49	5.22E-04	2.81E-02
positive regulation of cell proliferation (GO:0008284)	688	83	55.81	+	1.49	7.56E-04	3.79E-02
regulation of molecular function (GO:0065009)	2596	312	210.57	+	1.48	3.28E-12	2.23E-09
plasma membrane bounded cell projection organization (GO:0120036)	926	111	75.11	+	1.48	1.19E-04	8.15E-03
positive regulation of cell communication (GO:0010647)	1385	166	112.34	+	1.48	1.79E-06	2.23E-04
regulation of catalytic activity (GO:0050790)	1923	230	155.98	+	1.47	1.05E-08	2.76E-06
regulation of multicellular organismal process (GO:0051239)	2364	282	191.75	+	1.47	1.32E-10	6.61E-08
cell surface receptor signaling pathway (GO:0007166)	1744	208	141.46	+	1.47	7.87E-08	1.62E-05
positive regulation of signaling (GO:0023056)	1393	166	112.99	+	1.47	2.43E-06	2.97E-04
cellular developmental process (GO:0048869)	2782	331	225.66	+	1.47	1.80E-12	1.35E-09
system process (GO:0003008)	1066	126	86.47	+	1.46	7.76E-05	5.65E-03
vesicle-mediated transport (GO:0016192)	1518	178	123.13	+	1.45	2.24E-06	2.78E-04
negative regulation of protein metabolic process (GO:0051248)	904	106	73.33	+	1.45	4.23E-04	2.39E-02
multicellular organism development (GO:0007275)	3757	439	304.75	+	1.44	4.07E-16	1.22E-12
negative regulation of cellular protein metabolic process (GO:0032269)	851	99	69.03	+	1.43	7.51E-04	3.78E-02
cell communication (GO:0007154)	3741	435	303.45	+	1.43	1.48E-15	3.69E-12
signal transduction (GO:0007165)	3413	396	276.84	+	1.43	8.96E-14	1.22E-10
cellular response to endogenous stimulus (GO:0071495)	932	108	75.60	+	1.43	5.09E-04	2.75E-02
anatomical structure development (GO:0048856)	4039	468	327.62	+	1.43	8.93E-17	3.35E-13
response to external stimulus (GO:0009605)	1434	166	116.32	+	1.43	1.07E-05	1.03E-03
response to endogenous stimulus (GO:0009719)	1125	130	91.25	+	1.42	1.44E-04	9.50E-03
signaling (GO:0023052)	3650	421	296.07	+	1.42	2.31E-14	3.84E-11
cell projection organization (GO:0030030)	964	111	78.19	+	1.42	4.99E-04	2.71E-02
regulation of response to stimulus (GO:0048583)	3256	374	264.11	+	1.42	3.05E-12	2.18E-09
developmental process (GO:0032502)	4313	493	349.85	+	1.41	6.80E-17	3.40E-13
cellular response to organic substance (GO:0071310)	1764	200	143.09	+	1.40	3.88E-06	4.47E-04
regulation of biological quality (GO:0065008)	3127	354	253.64	+	1.40	8.27E-11	4.59E-08
multicellular organismal process (GO:0032501)	4793	540	388.78	+	1.39	6.96E-18	5.22E-14
regulation of immune system process (GO:0002682)	1062	119	86.14	+	1.38	8.60E-04	4.16E-02
positive regulation of cellular component organization (GO:0051130)	1057	118	85.74	+	1.38	1.03E-03	4.80E-02
positive regulation of response to stimulus (GO:0048584)	1713	190	138.95	+	1.37	2.49E-05	2.06E-03
response to organic substance (GO:0010033)	2252	246	182.67	+	1.35	3.09E-06	3.59E-04
regulation of apoptotic process (GO:0042981)	1260	137	102.20	+	1.34	9.81E-04	4.64E-02
regulation of programmed cell death (GO:0043067)	1273	138	103.26	+	1.34	1.04E-03	4.81E-02
cellular response to chemical stimulus (GO:0070887)	2153	233	174.64	+	1.33	1.21E-05	1.15E-03
regulation of cell death (GO:0010941)	1376	148	111.61	+	1.33	8.95E-04	4.30E-02
response to chemical (GO:0042221)	3040	326	246.59	+	1.32	1.85E-07	3.31E-05
regulation of cellular protein metabolic process (GO:0032268)	2132	228	172.94	+	1.32	3.45E-05	2.76E-03
regulation of protein metabolic process (GO:0051246)	2292	244	185.91	+	1.31	2.00E-05	1.71E-03
cellular response to stimulus (GO:0051716)	4737	498	384.24	+	1.30	6.02E-11	3.47E-08
immune system process (GO:0002376)	1813	190	147.06	+	1.29	4.89E-04	2.67E-02
positive regulation of cellular process (GO:0048522)	4248	436	344.57	+	1.27	6.34E-08	1.36E-05
response to stress (GO:0006950)	2641	267	214.22	+	1.25	2.28E-04	1.43E-02
response to stimulus (GO:0050896)	5945	600	482.23	+	1.24	8.56E-11	4.43E-08
positive regulation of biological process (GO:0048518)	4741	474	384.56	+	1.23	2.65E-07	4.37E-05
negative regulation of cellular process (GO:0048523)	3791	373	307.50	+	1.21	5.22E-05	3.97E-03
localization (GO:0051179)	4494	442	364.53	+	1.21	5.45E-06	5.92E-04
regulation of cellular process (GO:0050794)	8281	798	671.71	+	1.19	4.16E-12	2.71E-09
negative regulation of biological process (GO:0048519)	4260	410	345.55	+	1.19	1.26E-04	8.45E-03
regulation of biological process (GO:0050789)	8845	832	717.46	+	1.16	1.94E-10	9.11E-08
biological regulation (GO:0065007)	9384	872	761.18	+	1.15	3.50E-10	1.54E-07
cellular process (GO:0009987)	11157	970	904.99	+	1.07	6.15E-05	4.57E-03
biological_process (GO:0008150)	13525	1140	1097.07	+	1.04	2.28E-04	1.43E-02
Unclassified (UNCLASSIFIED)	1873	109	151.93	-	.72	2.28E-04	1.44E-02
nucleobase-containing compound metabolic process (GO:0006139)	2679	151	217.31	-	.69	7.55E-07	1.06E-04
organic cyclic compound metabolic process (GO:1901360)	2998	168	243.18	-	.69	7.69E-08	1.62E-05
heterocycle metabolic process (GO:0046483)	2810	156	227.93	-	.68	1.29E-07	2.41E-05
cellular aromatic compound metabolic process (GO:0006725)	2835	157	229.96	-	.68	9.30E-08	1.84E-05
cellular nitrogen compound metabolic process (GO:0034641)	3213	177	260.62	-	.68	5.69E-09	1.64E-06
gene expression (GO:0010467)	1825	92	148.03	-	.62	5.92E-07	8.37E-05
nucleic acid metabolic process (GO:0090304)	2111	101	171.23	-	.59	3.23E-09	9.87E-07
RNA metabolic process (GO:0016070)	1526	72	123.78	-	.58	4.19E-07	6.35E-05
amide biosynthetic process (GO:0043604)	489	19	39.66	-	.48	5.75E-04	3.03E-02
translation (GO:0006412)	375	12	30.42	-	.39	3.89E-04	2.24E-02
peptide biosynthetic process (GO:0043043)	393	12	31.88	-	.38	1.22E-04	8.26E-03
ncRNA metabolic process (GO:0034660)	499	15	40.48	-	.37	1.19E-05	1.14E-03
mRNA processing (GO:0006397)	435	13	35.28	-	.37	3.80E-05	3.01E-03
RNA splicing (GO:0008380)	372	11	30.17	-	.36	1.66E-04	1.08E-02
mRNA metabolic process (GO:0016071)	643	19	52.16	-	.36	3.51E-07	5.65E-05
nucleic acid phosphodiester bond hydrolysis (GO:0090305)	263	7	21.33	-	.33	9.63E-04	4.58E-02
RNA processing (GO:0006396)	798	21	64.73	-	.32	6.10E-10	2.34E-07
ncRNA processing (GO:0034470)	356	7	28.88	-	.24	4.13E-06	4.70E-04
macromolecule methylation (GO:0043414)	212	4	17.20	-	.23	3.84E-04	2.25E-02
methylation (GO:0032259)	263	4	21.33	-	.19	1.76E-05	1.55E-03
mRNA splicing, via spliceosome (GO:0000398)	279	4	22.63	-	.18	6.09E-06	6.57E-04
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)	279	4	22.63	-	.18	6.09E-06	6.53E-04
RNA splicing, via transesterification reactions (GO:0000375)	282	4	22.87	-	.17	4.21E-06	4.71E-04
ribonucleoprotein complex subunit organization (GO:0071826)	232	3	18.82	-	.16	2.68E-05	2.20E-03
ribosome biogenesis (GO:0042254)	275	3	22.31	-	.13	1.47E-06	1.90E-04
ribonucleoprotein complex assembly (GO:0022618)	219	2	17.76	-	.11	8.49E-06	8.66E-04
rRNA metabolic process (GO:0016072)	224	2	18.17	-	.11	9.15E-06	9.27E-04
RNA phosphodiester bond hydrolysis (GO:0090501)	135	1	10.95	-	.09	4.76E-04	2.65E-02
ribonucleoprotein complex biogenesis (GO:0022613)	425	3	34.47	-	.09	3.99E-11	2.40E-08
rRNA processing (GO:0006364)	199	1	16.14	-	.06	4.72E-06	5.25E-04